Standardization of single herb capsules of Manjistha, Kokam and Punarnava with assessment of their Nutritional value
Hardik K. Soni*, Bhavik R. Shah, Surendra B. Bhatt, Navin R. Sheth
1. Vasu Research Centre, A Division of Vasu Health care Pvt. Ltd., 896/A, G.I.D.C., Makarpura,Vadodara-390010, Gujarat, India
2. Department of Pharmaceutical Sciences, Saurashtra University, Rajkot-360005, Gujarat, India
Received on: 19-04-2010; Revised on: 12-05-2010; Accepted on:17-07-2010
Herbal supplements are more popular for improvement of primary healthcare as they are turning to natural remedies. Looking to this aspect, determination of nutritional value is essential for every herbal supplements. In this research work an attempt was made to establish system of standardization of herbal supplements like manjistha, kokam, and punarnava in order to assess the quality of the drugs. Powder characteristic and various quality control parameters were performed. Data of quality control parameters showed that the extracts used in formulation were of good in quality. HPTLC analysis indicates all extracts were derived from genuine parts of the plant. Concentration of lead, arsenic, cadmium and mercury in selected capsules and extract passes the limit for heavy metal content. Microbial analysis data revealed that Manjistha, Kokam and Punarnava had shown < 10 cfu/gm total bacterial counts. Total yeast and mould count, and the pathogens like E. coli, Salmonella, P. aeruginosa and S. aureus were absent in all selected capsules. Data of Nutritional value revealed that Manjistha capsule contain carbohydrate 93.82%, protein 3.06% and cholesterol 2.58%. While Kokam, and Punarnava capsule contain carbohydrate 86.60% and 83.13%, protein 3.24% and 7.19% and cholesterol 2.62% and 2.51%, respectively. From the obtained data we concluded that all the selected capsules and extracts were consistent with various quality and purity parameters. Nutritional assessments of the each capsule indicate all the drugs have good dietary supplement value and medicinal role as an herbal supplement.
Key words: Herbal supplements, Nutritional assessment, HPTLC, Heavy metal